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From WiX Wiki at MindCapers

<Wix xmlns="http://schemas.microsoft.com/wix/2006/wi" xmlns:util="http://schemas.microsoft.com/wix/UtilExtension">

   <InstallExecuteSequence>
     <Custom Action="WixCloseApplications" Before="InstallValidate" />
   </InstallExecuteSequence>

   <util:CloseApplication Id="CloseIE " CloseMessage="yes" Target="iexplore.exe " ElevatedCloseMessage="no" RebootPrompt="no" />